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$BCN<1H/8+K!$K$h$kC5:wE*%G!<%?2r@O(B
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$B")(B662 $B@>5\;T>e%v86(B 1-1-155 E-mail:oyama@kgupyr.kwansei.ac.jp
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keyword{Medical diagnosis, Structure activity relationship, IDIS, Datalogic/R}

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$B%;%_%Q%i%a%H%j%C%/2s5"LdBj$K$*$1$k(B $B%9%W%i%$%sJ?3j2=(B
$B:dK\!!OK(B:$BBg:eBg3XBg3X1!(B $B4pAC9)3X8&5f2J(B $B?tM}7O@l96(B $BE}7W?tM}9V:B(B E-mail: sakamoto@sigmath.es.osaka-u.ac.jp
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$B")(B560 $BBg:eI\K-Cf;TBT7s;3D.(B 1-3 (Tel. 06-850-6490)$B!!(B
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keyword{Nonparametric regression, Semiparametric regression model, Spline smoothing, Penalized least squares, Cross-validation}

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$B%Y%-JQ49$NJQ49<\EY$NITJQ2=D4@0(B
$B_@:j(B $B=S8w(B:$B%U%!%$%6!<@=Lt3t<02q$B")(B163-04 $B?7=I6h@>?7=I(B 2-1-1$B?7=I;00f(B $B%S%kFb;d=qH"(B226$B9f(B (Tel. 03-5381-5772)
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$B")(B650 $BK-Cf;TBT7s;3D.(B 1-3 (Tel. 06-850-5688)
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keyword{Ordinary power transformation, Normalizing power transformation, Jacobian of transformation, Relative change rate}

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$BN%;6JQ?t%i%s%@%`;~7ONs$N3NN(M}O@(B ---$B0LAj<~4|$H$=$N3NN((B ---
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$B")(B701-01 $BARI_;T>>Eg(B 577 (Tel. 086-462-1111)
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$B7WNLJ88%3X$NNr;K$H2]Bj(B
$BB<>e@,>!(B:$BE}7W?tM}8&5f=j$*$h$SAm9g8&5fBg3X1!Bg3X(B
$B")(B106 $BEl5~ET9A6hFnKcI[(B 4-6-7 E-mail:murakami@ism.ac.jp
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